Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement

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Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement.

BACKGROUND Total knee arthroplasty (TKA) is often carried out using a tourniquet and shed blood is collected in drains. Tranexamic acid decreases the external blood loss. Some blood loss may be concealed, and the overall effect of tranexamic acid on the haemoglobin (Hb) balance is not known. METHODS Patients with osteoarthrosis had unilateral cemented TKA using spinal anaesthesia. In a double...

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Additional Dose of Intravenous Tranexamic Acid after Primary Total Knee Arthroplasty Further Reduces Hidden Blood Loss

Background Total knee arthroplasty (TKA) is the most frequently performed procedure in treating advanced knee osteoarthritis. Excessive perioperative blood loss can sometimes lead to postoperative anemia. Tranexamic acid (TXA) is a potent fibrinolysis inhibitor which has been extensively used at the surgical incision and closure to lower overall blood loss in adult reconstruction surgery. Our p...

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Tranexamic acid decreases blood loss in shoulder arthroplasty

BACKGROUND The objective of this meta-analysis was to evaluate the efficacy and safety of tranexamic acid (TXA) in shoulder arthroplasty (SA). METHODS Academic articles were identified from the Cochrane Library, Medline (1966-2017.2), PubMed (1966-2017.2), Embase (1980-2017.2), and ScienceDirect (1966-2017.2). Randomized controlled trials (RCTs) and non-RCTs studying TXA in SA were included. ...

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Effect of Tranexamic Acid on Blood Loss and Blood Transfusion Reduction after Total Knee Arthroplasty

PURPOSE Total knee arthroplasty (TKA) accompanies the risk of bleeding and need for transfusion. There are several methods to reduce postoperative blood loss and blood transfusion. One such method is using tranexamic acid during TKA. The purpose of this study was to confirm whether tranexamic acid reduces postoperative blood loss and blood transfusion after TKA. MATERIALS AND METHODS A total ...

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Tranexamic acid reduces blood loss after knee arthroplasty.

We welcome letters to the Editor concerning articles which have recently been published. Such letters will be subject to the usual stages of selection and editing; where appropriate the authors of the original article will be offered the opportunity to reply. Letters should normally be under 300 words in length, double-spaced throughout, signed by all authors and fully referenced. The edited ve...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2003

ISSN: 0007-0912

DOI: 10.1093/bja/aeg111